For several years doctors, have said how and where fat is deposited can affect our general health. For example, those who have fat deposits in the mid-section, or visceral fat, are at greater risk for heart disease and diabetes. Visceral fat deposits around the organs, which can attract a particular cell called a macrophage (M1) that gives off a protein to promote insulin resistance.

Researchers at Oxford University and the French Institute of Health and Medical Research have found another protein called interferon regulatory factor-5 (IRF-5) that seems to tame the M1 macrophage. To see if it was truly beneficial, the researchers had the help of genetically engineered mice that did not have the IRF-5 gene and ate a high fat diet or a healthy one.

Although the mice that ate the high fat diet did gain weight, the fat distribution was different. Instead of being around visceral organs, the fat deposits were under the skin and the mice were healthy.
Although more work needs to be done, the researchers are hoping this is another weapon in the fight of obesity.
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