Animals Behind Top Drugs

Animal testing and research is behind nearly every prescription medicine.

Are you taking a prescription medicine?

Nearly every prescription medicine available has depended on animal testing and research.

Animal testing is essential for understanding the safety and proper dosages of new medicines and treatments. If researchers find that a drug is safe and effective through animal testing, they can begin testing it in small groups of people and then larger groups of people. Both extensive human and animal testing is required by law before a drug can be approved. The U.S. Food and Drug Administration requires animal testing before there can be clinical drug trials in people. Learn more about which lab animals have contributed to the most common prescription drugs in the chart below.

A chemotherapy drug
RankDrugDrug UsageSpecies
1SynthroidEnlarged thyroid; hypothyroidismRats, Dogs, Mice
2CrestorHigh cholesterolRats, Beagle dogs, Mice, Cats, Cynomolgus monkeys, Rabbits
3NexiumHeartburn; Acid RefluxRats, Beagle dogs, Rabbits, Mice
4Ventolin HFABronchospasmRats, Beagle dogs, New Zealand white rabbits
5Advair DiskusAsthma; COPD Flare-upsRats, Dogs, Mice, Rabbits, Guinea pigs, Monkeys, Hamsters
6DiovanHigh Blood PressureRats, Mice, Rabbits, Marmosets
7Lantus SolostarDiabetes mellitusRats, Beagle Dogs, Rabbits, Guinea Pigs
8CymbaltaFibromyalgia; Major Depressive & General Anxiety DisordersMice, Rats, Rabbits, Dogs
9VyvanseADHD; Severe binge eating (adults)Rats, Guinea Pigs, Beagle Dogs
10LyricaFibromyalgia; EpilepsyMice, Rats, Monkeys, Rabbits
11Spiriva HandihalerCOPD (including Bronchitis & Emphysema)Mice, Rats, Rabbits, Dogs
12LantusTypes 1 & 2 DiabetesMice, Dogs, Guinea Pigs, Rats
13CelebrexArthritis; Ankylosing SpondylitisRats, Mice, Beagle Dogs, Monkeys
14AbilifySchizophrenia & Bipolar DisorderRats, Dogs, Monkeys, Rabbits
15JanuviaType 2 DiabetesRats, Rabbits, Dogs, Monkeys
16NamendaModerate to Severe DementiaRats, Mice, Beagle Dogs
17ViagraErectile DysfunctionRats, Dogs, Mice, Rabbits
18CialisErectile DysfunctionMice, Beagle Dogs, Wistar Rats
19ZetiaHigh cholesterolRats, Dogs, Mice
20NasonexSeasonal/Year Round AllergiesRats, Rabbits, Dogs
21Suboxone Narcotic AddictionMice, Rats, Rabbits, Baboons, Dogs
22SymbicortAsthmaMice, Rats, Dogs
23BystolicHypertensionMice, Rats, Dogs
24Flovent HFAPrevent Asthma AttacksRats, Rabbits, Dogs
25OxycontinLong lasting, Moderate to Severe PainRats, Rabbits
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