One million people live with Parkinson’s disease in the United States. Symptoms can range from a small tremor to slow movement, balance problems and could include gastrointestinal problems. It is a progressive neurodegenerative disease that results from the loss of the neurotransmitter dopamine. Although there are many drugs available, none slow or stop the process of Parkinson ’s disease
Great news on the research front! Researchers at the University of Alabama Birmingham are working with a new class of drugs called kinase inhibitors to treat rats that have Parkinson ’s disease. These rats have degeneration from the loss of dopamine and build-up of a substance called alpha-synuclein, just like their human counterparts.
Many drugs do not get across the blood brain barrier, a natural defense to protect the brain against disease, however in order to treat Parkinson’s and other neurodegenerative diseases, it is imperative that drugs get to the proper place for treatment. This kinase inhibitor does just that, and preliminary results in the rats have shown that it protected the brain against neurodegeneration, lessened inflammation, and completely stopped neuron loss.
Check out this ground breaking research at www.uab.edu/news/innovation/item/6225-potential-drug-lessens-neurodegeneration-in-parkinson-s-disease-model
Parkinson ’s disease info at http://www.pdf.org/en/meds_treatments