Anyone who has had an asthma attack – or watched your child have one – knows how frightening it can be. A rescue inhaler can, quite literally, be a life saver. β2-agonists are the most common agents in rescue inhalers, but they can lose their efficacy the more a patient uses them. Of course, this presents a major problem for long term management of symptoms.
Researchers from Canada and Australia collaborated to study use of nebulized perflubron and carbon dioxide to see if this would be an effective rescue method for acute asthma attacks. In their study, they sensitized sheep to house dust mites. Once sensitized, they were able to induce asthma which was then treated with the nebulized perflubron and carbon dioxide. The treatment rapidly opened the constricted airways, which means it was effective. As an added bonus, “perflubron has been shown to reduce pulmonary inflammation and injury.”
This is exciting news for asthma sufferers who depend on their rescue inhalers in times of acute attacks!