Foundation for Biomedical Research
Ethical Science for People and Animals

Animal Research: Guided by Rigorous Laws and Oversight

Animal testing and research are governed by some of the world’s strictest regulations — often more stringent than those for human studies. These laws ensure humane treatment, scientific integrity, and full accountability at every level.

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Strict Federal Oversight

How U.S. Law Protects Animals in Research

Animal research in the U.S. is governed by a comprehensive network of federal laws and institutional protocols. The Animal Welfare Act ensures high standards for care, housing, and medical treatment. Oversight bodies like Institutional Animal Care and Use Committees (IACUCs) — which include veterinarians and independent community members — are legally required to review and approve every research proposal. Additionally, the Public Health Service Act mandates strict adherence to animal care guidelines for institutions receiving federal research funds. Together, these regulatory oversight systems ensure humane and responsible research practices.

Learn More

To learn more about the oversight of animal testing and research, visit the National Association for Biomedical Research’s website.

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Ethical Oversight in Action

What Are IACUCs and Why They Matter

Every U.S. research institution that works with animals is legally required to form an Institutional Animal Care and Use Committee (IACUC). These independent committees review and approve all animal research to ensure ethical treatment and scientific necessity. Each IACUC includes a veterinarian and at least one community member unaffiliated with the institution. They evaluate whether researchers are using the fewest animals possible and selecting the most suitable species. With the authority to reject proposals or halt ongoing projects, IACUCs serve as a critical safeguard for humane animal care.

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Since 1981, FBR has championed ethical animal research to drive innovation in medicine. Your support helps us continue educating the public and empowering the research community to improve lives across species.

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